The church began as an English-speaking fellowship in the Baptist Reading Room, Kumasi on the 19^th day of July 1964 at the invitation of two Baptist missionaries namely Rev. Maurice Smith and Miss Evelyn Stone who also led the fellowship up to June 1965. Rev. Maurice Smith was replaced by Rev. W.A. Arnold at a time the number of baptized members of the fellowship had risen to 60.

In 1967, after Rev. Maurice Smith had finally left Ghana for Furlough in America, Mr. Emmanuel Ephraim was elected leader of the fellowship and it was under his leadership that the fellowship was organized as a church called Grace Baptist Church on 30^th June 1968 with 68 members.

In November, 1969, the church started a search for a plot of land for the construction of a church building. The focus or target was on the parcel of land currently occupied by Americana Hotel and Mid Country Chapel. When it became apparent that our efforts in getting that particular land would not succeed, fortune smiled on Grace Baptist Church, when in a rather painful manner the Aliens Compliance Order was invoked by the government of Ghana to flush out all illegal immigrants.

This decision led to the exit from Ghana of virtually all the Yorubas who constituted the membership of Ebenezer Baptist Church, whose auditorium and Sunday school buildings under construction were nearing completion at our present site. These buildings were entrusted to the Field Evangelist, Rev. Smith at whose request Grace Baptist Church agreed to assume responsibility for the completion of the construction work on the building and their furnishing with the view to moving in for worship service and Bible Studies. Grace Baptist Church finally moved into the building on February 2, 1970 whilst their construction and furnishing were completed in June 1970 together with the landscaping.

In the light of the forgoing paragraphs, Grace Church consulted a Law firm J.J. Peele with the view to formalizing and regularizing the change that had occurred so that transfer of the property from Ebenezer to Grace would be properly effected. The conveyance procedure was followed but the erstwhile leadership of Ebenezer had obviously scattered to different parts of Nigeria thus no coherent response was forthcoming from them. The practical steps taken in this matter are well documented.  Up to this time, the church had remained a strictly English speaking one. 

The remnant of Ebenezer Baptist Church members were active participants in all the programmes of Grace Baptist Church. This fact influenced and indeed occasioned the decision to introduce ‘Twi’ into the activities of the church, especially in the Christian Education Department.

Rev. Samuel Akuamoah, the first Ghanaian full-time pastor, was inducted into office in 1975. His appointment, however, was short-lived as he resigned the following year and returned to the United States of America. The mantle of leadership then fell on Rev. Mike Shockley, a Baptist missionary who was a lecturer at the Abuakwa Seminary. He was asked to pastor in 1977. After him came Brothers Frank Kankam and Frank Adams as church leader and associate church leader respectively. Their leadership was also cut short by their decisions to resign and concentrate on their studies at the Ghana Baptist Seminary, Abuakwa where they were being trained as pastors. Rev. Dr. J.A. Boadi was, therefore, invited to pastor the Church. He was also a lecturer at the Seminary at Abuakwa and therefore assisted the church on a part-time basis.

After his seminary education at Abuakwa, in 1981; Pastor Frank Adams was called to pastor the church. Under the able leadership of Rev. Frank Adams, the church embarked on church planting and two churches- Asokwa and Nkawie Baptist Churches were established in 1982 whilst three others- Bomso (Victory), Buokrom and Fumesua Baptist Churches were also established in 1984.

As the work-load became heavier, the need for a second pastor became urgent, so, Rev. Kojo Osei-Wusuh was invited from USA to take up an appointment as Associate Pastor in 1985. In 1984, however, the need to give secular education with a Christian background to children of church members to save them from heavy doses of cultural diet which were then being forced down the throats of children in public schools, led to the commencement of the kindergarten level of a preparatory school. This school is now up to Junior High School Three (JHS) 3. As a point of interest, work was started and completed on a three-classroom block to fully house the then blossoming Preparatory School. An office and a library were also built into this block. A three-storey block has also been completed after the Silver Jubilee which is currently accommodating JHS students.

Just as Rev. Osei-Wusuh was settling down, Rev. Frank Adams had to leave suddenly for further studies in Switzerland in 1985. The Church was once more left with only one minister. The heavy task that would have otherwise been placed on the shoulders of Rev. Osei-Wusuh alone was attenuated by the streamlining of the administrative structure of the church. The then Executive Committee (the highest decision-making body) was replaced with two bodies viz: Body of Deacons and the Church Council. Nine brethren were ordained as deacons to assist the pastor in handling the spiritual affairs of the Church whilst the Church Council, constituted mainly by church group leaders and committee chairmen, was to assist with the administrative work. Another body created over the past 2 years to support ministry in the church is pastoral Assistants.